Acne is a common symptom related to menopause transition. You may experience acne during perimenopause as a result of a decrease in estrogen levels or an increase in testosterone. Prescription medication (like prescribed retinoids, birth control pills and spironolactone) is often used to successfully treat acne resulting from menopause. There are also natural/non-pharmaceutical approaches for treating menopausal acne, like Tea Tree Oil, Alpha Hydroxy Acid (AHA) and a plant-based diet.